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A train rockets across Eastern Europe. On board are agent Jacques Kristoff and Galina Konstantin (Laura Elena Harring from JOHN Q), a beautiful high-tech thief. Holding the passengers of train 681 hostage is Mason Cole (Tomas Arana from GLADIATOR) and his band of terrorists who have come to steal a powerful bioweapon hidden on board. With the train out of control and on a collision course with danger, Kristoff must become a one-man army – taking on the terrorists to save the lives of everyone on board and the millions who would die if the deadly virus is unleashed.