Flirty, flaky party girl Maggie (Cameron Diaz) and plain, dependable lawyer Rose (Toni Collette) are sisters, best friends and bitter rivals who seem to have only two things in common – DNA and size 8 ½ feet. Only when their love-hate relationship veers towards the hate end of the spectrum do they accidentally discover they also share a long-lost grandmother (Shirley MacLaine) who enriches their lives and helps them make peace with each other – and themselves.
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Cameron Diaz, Toni Collette, Shirley MacLaine, Mark Feuerstein, Richard Burgi, Brooke Smith, John Mastrangelo Sr., Anson Mount, Ken Howard, Candice Azzara, Jason Peck, Kateri DeMartino, Brandon Karrer, Eric Balfour, Nicole Randall Johnson, Emilio Mignucci, Norman Lloyd, Francine Beers, Jackie Geary, Jerry Adler, Marcia Jean Kurtz, Carlease Burke, Alan Blumenfeld, Andy Powers, David Shatraw, Mary-Pat Green, Carol Florence, Dan Fitzgerald, Benton Jennings, Chihiro Kawamurra, Jill Saunders, Karen Vicks, Terrance Christopher Jones, Maureen Solomon, Ivana Milicevic.