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A night of wild partying ends in disaster when janitor Kenneth falls into a drug-induced coma. Fearing their future reputations, a group of med students abandon the body outside a hospital. Racked by guilt, good girl Catherine (Arielle Kebbel, Gilmore Girls) secretly attempts to revive him, but accidentally administers a rare chemical allowing Kenneth to possess random strangers bodies and exact revenge on those who wronged him. Can Catherine find a cure before shes next?