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Dr. Michael Glass (David Morrissey), a respected London criminal psychiatrist, is brought in by Scotland Yard detective Roy Washburn (David Thewlis) to perform a psychiatric evaluation of crime novelist Catherine Tramell (Sharon Stone), following the death of a sports star in her presence. Physically drawn to Tramell and mentally intrigued by her, Glass, against the advice of his mentor, Dr. Milena Gardosh (Charlotte Rampling), is quickly sucked into her web of lies and seduction. A deadly battle of wits ensues, while several people around them also die in mysterious circumstances. Can Glass avoid suspicion; is Washburn implicated; does Catherine write true fictions?